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Guang Lei Selected Research

4,5-dihydroorotic acid

1/2021DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer.

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Guang Lei Research Topics

Disease

28Neoplasms (Cancer)
05/2024 - 01/2019
2Starvation
01/2023 - 01/2020
2Ovarian Neoplasms (Ovarian Cancer)
01/2023 - 01/2021
2Lung Neoplasms (Lung Cancer)
01/2022 - 06/2021
2Cysts
11/2021 - 01/2021
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2021 - 01/2020
1Breast Neoplasms (Breast Cancer)
03/2024
1Insulin Resistance
01/2023
1Endophthalmitis (Ophthalmia)
01/2022
1Hepatocellular Carcinoma (Hepatoma)
01/2022
1Mucormycosis
01/2022
1Melanoma (Melanoma, Malignant)
01/2021
1Adenocarcinoma of Lung
01/2020
1Disease Progression
01/2020
1Stomach Neoplasms (Stomach Cancer)
01/2019

Drug/Important Bio-Agent (IBA)

5Proteins (Proteins, Gene)FDA Link
01/2023 - 01/2021
4DisulfidesIBA
01/2023 - 01/2020
4Cystine (L-Cystine)IBA
01/2023 - 01/2020
4Glucose (Dextrose)FDA LinkGeneric
01/2023 - 01/2020
3IronIBA
04/2024 - 11/2021
3Poly(ADP-ribose) Polymerase InhibitorsIBA
03/2024 - 01/2021
3NADP (NADPH)IBA
01/2023 - 01/2020
3Facilitative Glucose Transport Proteins (Glucose Transporter)IBA
01/2023 - 01/2020
3Mechanistic Target of Rapamycin Complex 1IBA
11/2021 - 01/2021
2Lipid PeroxidesIBA
04/2024 - 01/2021
2Phospholipid Hydroperoxide Glutathione PeroxidaseIBA
03/2024 - 01/2021
2Dihydroorotate DehydrogenaseIBA
08/2021 - 01/2021
1Voltage-Dependent Anion ChannelsIBA
03/2024
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
03/2024
1erastinIBA
03/2024
1Antimitotic AgentsIBA
01/2024
1Angiogenesis InhibitorsIBA
01/2023
1Actins (F Actin)IBA
01/2023
1Hormones (Hormone)IBA
01/2023
1Insulin (Novolin)FDA Link
01/2023
1Radioisotopes (Radionuclides)IBA
01/2023
1Messenger RNA (mRNA)IBA
01/2023
1GhrelinIBA
01/2023
1beta CateninIBA
01/2022
1UbiquinoneIBA
01/2022
1Kelch-Like ECH-Associated Protein 1IBA
01/2022
1Amphotericin B (Amphotericin)FDA LinkGeneric
01/2022
1gossypol acetic acidIBA
12/2021
1Phospholipids (Phosphatides)FDA LinkGeneric
11/2021
1Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
11/2021
1TOR Serine-Threonine KinasesIBA
11/2021
1Transcription Factors (Transcription Factor)IBA
06/2021
14,5-dihydroorotic acidIBA
01/2021
1olaparibIBA
01/2021
1Aspartic Acid (Aspartate)FDA Link
01/2021
1Sunitinib (Sutent)FDA Link
01/2021
1pyrimidineIBA
01/2021
1UridineIBA
01/2021
1Radiation-Sensitizing AgentsIBA
01/2021
1Monoclonal AntibodiesIBA
01/2021
1Polycomb Repressive Complex 1IBA
01/2020
1Vinorelbine (Navelbine)FDA LinkGeneric
01/2020
1AMP-Activated Protein KinasesIBA
01/2020
1ChromatinIBA
01/2020
1apatinibIBA
01/2020
1Histones (Histone)IBA
01/2020
1Cysteine (L-Cysteine)FDA Link
01/2020
1CollagenIBA
01/2019
1ParaffinIBA
01/2019
1Formaldehyde (Formol)FDA Link
01/2019

Therapy/Procedure

12Therapeutics
04/2024 - 01/2021
6Radiotherapy
05/2024 - 01/2020
5Immunotherapy
04/2024 - 11/2021
2Drug Therapy (Chemotherapy)
01/2023 - 01/2020
1Debridement
01/2022